Chuanrui Ma Selected Research

T0901317

1/2021	Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
1/2021	Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removes LXR-induced lipogenesis.
1/2020	Combination of MEK1/2 inhibitor and LXR ligand synergistically inhibit atherosclerosis in LDLR deficient mice.
12/2018	Activation of liver X receptor plays a central role in antiviral actions of 25-hydroxycholesterol.

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Chuanrui Ma Research Topics

Disease

15	Atherosclerosis 01/2022 - 01/2016
9	Inflammation (Inflammations) 01/2022 - 01/2017
6	Fatty Liver 05/2021 - 01/2018
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 10/2019
4	Neoplasms (Cancer) 01/2021 - 10/2018
4	Cholestasis 01/2021 - 01/2019
3	Coronary Disease (Coronary Heart Disease) 01/2020 - 03/2016
3	Diabetic Nephropathies (Diabetic Nephropathy) 01/2020 - 01/2018
2	Non-alcoholic Fatty Liver Disease 01/2022 - 05/2020
2	Wounds and Injuries (Trauma) 12/2021 - 01/2017
2	Obesity 05/2021 - 01/2020
2	Intrahepatic Cholestasis 01/2021 - 01/2020
2	Dyslipidemias (Dyslipidemia) 01/2020 - 01/2020
2	Vascular Diseases (Vascular Disease) 01/2020 - 01/2019
1	Myocardial Infarction 12/2021
1	Ischemia 12/2021
1	Type 2 Diabetes Mellitus (MODY) 11/2021
1	Hypertrophy 10/2021
1	Heart Failure 10/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2021
1	Carcinoma (Carcinomatosis) 01/2021
1	Fatigue 01/2021
1	Necrosis 01/2020
1	Hypertriglyceridemia 01/2020
1	Atherosclerotic Plaque (Atheroma) 01/2020
1	Insulin Resistance 10/2019
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2019
1	Breast Neoplasms (Breast Cancer) 12/2018
1	Neoplasm Metastasis (Metastasis) 12/2018
1	Infections 12/2018
1	Virus Diseases (Viral Diseases) 12/2018

Drug/Important Bio-Agent (IBA)

12	Apolipoproteins E (ApoE)IBA 01/2022 - 03/2016
9	LipidsIBA 01/2022 - 01/2017
4	Pharmaceutical PreparationsIBA 01/2022 - 01/2020
4	HydrogelsIBA 12/2021 - 01/2020
4	T0901317IBA 01/2021 - 12/2018
4	LigandsIBA 01/2021 - 12/2018
4	Liver X ReceptorsIBA 01/2021 - 01/2018
4	naoxintongIBA 10/2019 - 03/2016
3	ApolipoproteinsIBA 01/2022 - 03/2016
3	CholesterolIBA 01/2020 - 12/2018
3	Capsules (Microcapsules)IBA 10/2019 - 01/2018
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 05/2021
2	Metformin (Glucophage)FDA LinkGeneric 11/2021 - 01/2018
2	InterferonsIBA 01/2021 - 12/2018
2	tectorigeninIBA 01/2021 - 01/2020
2	U 0126 (UO 126)IBA 01/2021 - 01/2020
2	Sirtuin 1IBA 01/2021 - 01/2019
2	Peptides (Polypeptides)IBA 05/2020 - 01/2020
2	Fenofibrate (CiL)FDA LinkGeneric 05/2020 - 01/2019
2	formononetinIBA 01/2020 - 01/2019
2	IsoflavonesIBA 01/2020 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2018
2	buchang naoxintongIBA 01/2017 - 03/2016
1	Caspase 8 (Caspase-8)IBA 01/2022
1	7,3'-dihydroxy-4'-methoxyisoflavoneIBA 01/2022
1	TabletsIBA 01/2022
1	FlavonoidsIBA 01/2022
1	Chloroquine (Aralen)FDA LinkGeneric 01/2022
1	AntioxidantsIBA 01/2022
1	Huang QiIBA 01/2022
1	ginsenoside Rg3IBA 10/2021
1	Calcium-Transporting ATPases (Ca2+ ATPase)IBA 10/2021
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 10/2021
1	Glucose (Dextrose)FDA LinkGeneric 05/2021
1	danthronIBA 05/2021
1	Adiponectin ReceptorsIBA 05/2021
1	Urethane (Ethyl Carbamate)IBA 01/2021
1	pterostilbeneIBA 01/2021
1	3,5- diethoxycarbonyl- 1,4- dihydrocollidineIBA 01/2021
1	ZincIBA 01/2021
1	icariinIBA 01/2021
1	benzophenoneIBA 05/2020
1	Ketoprofen (Orudis)FDA LinkGeneric 05/2020
1	oxidized low density lipoproteinIBA 01/2020
1	Rosiglitazone (Avandia)FDA Link 01/2020
1	15-deoxyprostaglandin J2IBA 01/2020
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2020
1	Naproxen (Naprosyn)FDA LinkGeneric 01/2020
1	flavoneIBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020
1	Scavenger Receptors (Scavenger Receptor)IBA 01/2020
1	GlucokinaseIBA 10/2019
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 10/2019
1	Insulin Receptor Substrate ProteinsIBA 10/2019
1	obeticholic acidIBA 01/2019
1	Bile Acids and Salts (Bile Acids)IBA 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	LongShengZhiIBA 01/2019
1	Tamoxifen FDA LinkGeneric 12/2018
1	Estrogen ReceptorsIBA 12/2018
1	cholesterol 25-hydroxylaseIBA 12/2018
1	25-hydroxycholesterol 3-sulfateIBA 12/2018
1	Antiviral Agents (Antivirals)IBA 12/2018

Therapy/Procedure

2	Therapeutics 01/2021 - 01/2020
2	Oral Administration 01/2021 - 01/2021
1	Injections 12/2021
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2021
1	Subcutaneous Injections 01/2021